LEV, Belfast, Dublin


Microbiological Safety Cabinets

Microbiological safety cabinets (MSC) are particular types of LEV used laboratories to control biological agents, including pathogenic micro-organisms (including genetically modified micro-organisms), cell cultures and human and animal tissues and fluids.


As with other LEVs, MSCs fall under CoSHH reg 9 (UK). It is statutory for employers / LEV owners that thorough examination & testing is carried out at least once every 14months (or more frequently - CoSHH Schedule 4). Furthermore the employer / LEV owner must ensure to ensure all controls are maintained in an efficient state, an efficient working order, good repair & in a clean condition. For ROI, the Safety, Health and Welfare at Work Act 2005 applies.

BS EN 12469:2000 – Biotechnology. Performance criteria for microbiological safety cabinets.
BS5726:2005 – Siting of MSCs.

Class II & III MSCs may require particle counts in which case ISO 14644-1 ‘Cleanrooms & Associated Control Environments’ with time intervals set by ISO 14644-2, using international test methods published in ISO 14644-3 are applicable. HEPA filter testing is covered by PD 6609 ‘Environmental cleanliness in enclosed spaces – Guide to in situ high efficiency filter leak testing’.

EN12741 Biotechnology – ‘Labs for research, development and analysis’ provides guidance on isolators.



Other / optional tests may include

Reporting to HSG258 & BS EN 12469 criteria + marking systems with test labels.